Isolation of Id1 interaction protein in human prostate cancer / 中华男科学杂志
National Journal of Andrology
;
(12): 796-799, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-309792
ABSTRACT
<p><b>OBJECTIVE</b>To isolate the inhibitor of DNA binding 1 (Id1) interaction protein and to determine the role and action mechanism of Id1 in human prostate cancer.</p><p><b>METHODS</b>The expression vector pET-28a/Id1 was established and used as a bait to prey the interaction protein by pull-down assay.</p><p><b>RESULTS</b>A clear interaction protein band was observed by SDS-PAGE, which was found to be activating transcription factor 3 (ATF3) by Western blotting.</p><p><b>CONCLUSION</b>Id1 may play a role in human prostate cancer by interacting with ATF3.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neoplasias de la Próstata
/
ARN
/
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
/
Factor de Transcripción Activador 3
/
Proteína 1 Inhibidora de la Diferenciación
/
Genética
/
Metabolismo
Límite:
Humanos
/
Masculino
Idioma:
Chino
Revista:
National Journal of Andrology
Año:
2008
Tipo del documento:
Artículo
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