Correlation between the refractory periods and threshold potentials and the spike programming in cortical neurons / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 14-17, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-310817
ABSTRACT
<p><b>AIM</b>To investigate the intrinsic mechanisms underlying spike programming at pyramidal neurons and interneurons in layer II/III of sensorimotor cortex.</p><p><b>METHODS</b>Electrical signals at the cortical neurons were recorded in current clamp model with multi-clamp700B Amplifiers. Signals were inputted into pClamp and Origin for data acquisition and analyses.</p><p><b>RESULTS</b>Compared to pyramidal neurons, interneurons express the higher capacity of spikes and the more stability of spike programming, which are mechanistically caused by lower threshold potentials and shorter refractory periods.</p><p><b>CONCLUSION</b>The refractory periods and threshold potentials directly influence the programming of sequential spikes.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Periodo Refractario Electrofisiológico
/
Potenciales de Acción
/
Corteza Cerebral
/
Ratas Sprague-Dawley
/
Células Piramidales
/
Transmisión Sináptica
/
Técnicas de Placa-Clamp
/
Biología Celular
/
Umbral Diferencial
Límite:
Animales
Idioma:
Chino
Revista:
Chinese Journal of Applied Physiology
Año:
2008
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS