Clinical significance of transrectal ultrasound in detecting of rectal cancer margin and deciding of distal surgical incisal edge / 中华外科杂志
Chinese Journal of Surgery
;
(12): 279-281, 2004.
Artículo
en Chino
| WPRIM
| ID: wpr-311130
ABSTRACT
<p><b>OBJECTIVE</b>To study the role of transrectal ultrasound in detecting and deciding rectal cancer margin and surgical incisal edge.</p><p><b>METHODS</b>33 surgical specimens of rectal carcinoma were examined with transrectal ultrasound. Cancerous margin and surgical incisal edge were determined. The results were compared with pathological examination. p53 and K-ras gene mutation as tumor molecular markers of residue cancer cells were detected in incisal edge tissue with PCR-SSCP method.</p><p><b>RESULTS</b>General accuracy for cancer infiltration depth with transrectal ultrasound was 86.6%. For mucosa and submucosa infiltration lesions, the accuracy was 72.7%. For lamina muscularis, the accuracy was 90.9%. And for adventitia and peripheral tissue infiltration of rectum, the accuracy was 88.5% and 100% respectively. No remains of cancer cells and tumor molecular markers were detected at distal incisal edges of 1.0 cm, 2.0 cm and 3.0 cm determined with transrectal ultrasound.</p><p><b>CONCLUSIONS</b>Rectal cancer margine and surgical incisal edge determined with transrectal ultrasound are close to examined by pathology. Transrectal ultrasound is helpful and reliable to define incisal edge in rectal cancer surgery.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Neoplasias del Recto
/
Recto
/
Cirugía General
/
Diagnóstico por Imagen
/
Análisis Mutacional de ADN
/
Adenocarcinoma
/
Reacción en Cadena de la Polimerasa
/
Proteína p53 Supresora de Tumor
/
Genes ras
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Surgery
Año:
2004
Tipo del documento:
Artículo
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