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Stem Cells and Niemann Pick Disease
International Journal of Stem Cells ; : 30-32, 2014.
Artículo en Inglés | WPRIM | ID: wpr-31118
ABSTRACT
BACKGROUND AND

OBJECTIVES:

Niemann Pick A disease causes a progressive accumulation of sphyngomyelin in several organs and the survival of the patients is usually limited to three years. We describe the outcome of a patient suffering from Niemann Pick A disease, who first underwent an haploidentical bone marrow transplantation, and then intrathecal and I.V injections of mesenchymal cells. METHODS AND

RESULTS:

While the outcome of bone marrow transplantation was a complete failure, one month after the treatment with the mesenchymal cells the patient improved from the psychomotor and the parenchymal storage perspective. When hypersplenism was solved platelets rose quickly from 20,000 to 120,000/microliter.

CONCLUSIONS:

Therefore cellular therapy should be considered as a possible choice of treatment of NPA disease.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Células Madre / Enfermedades de Niemann-Pick / Trasplante de Médula Ósea / Hiperesplenismo Límite: Humanos Idioma: Inglés Revista: International Journal of Stem Cells Año: 2014 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Células Madre / Enfermedades de Niemann-Pick / Trasplante de Médula Ósea / Hiperesplenismo Límite: Humanos Idioma: Inglés Revista: International Journal of Stem Cells Año: 2014 Tipo del documento: Artículo