Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 225-231, 2009.
Artículo
en Inglés
| WPRIM
| ID: wpr-311887
ABSTRACT
<p><b>OBJECTIVE</b>To review the recent studies about human umbilical cord mesenchymal stem cells (hUCMSCs) and advances in the treatment of spinal cord injury. Data sources Published articles (1983 - 2007) about hUCMSCs and spinal cord injury were selected using Medline. Study selection Articles selected were relevant to development of mesenchymal stem cells (MSCs) for transplantation in spinal cord injury therapy. Of 258 originally identified articles 51 were selected that specifically addressed the stated purpose.</p><p><b>RESULTS</b>Recent work has revealed that hUCMSCs share most of the characteristics with MSCs derived from bone marrow and are more appropriate to transplantation for cell based therapies.</p><p><b>CONCLUSIONS</b>Human umbilical cord could be regarded as a source of MSCs for experimental and clinical needs. In addition, as a peculiar source of stem cells, hUCMSCs may play an important role in the treatment of spinal cord injury.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Fisiología
/
Traumatismos de la Médula Espinal
/
Terapéutica
/
Cordón Umbilical
/
Biología Celular
/
Trasplante de Células Madre
/
Células Madre Mesenquimatosas
/
Modelos Biológicos
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Chinese Medical Journal
Año:
2009
Tipo del documento:
Artículo
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