Inflammasome and its role in immunological and inflammatory response at early stage of burns / 中华烧伤杂志
Chinese Journal of Burns
; (6): 261-264, 2014.
Article
en Zh
| WPRIM
| ID: wpr-311957
Biblioteca responsable:
WPRO
ABSTRACT
Inflammasomes are large multi-protein complexes that serve as a platform for caspase-1 activation, and this process induces subsequent maturation and secretion of the proinflammatory cytokines IL-1β and IL-18, as well as pyroptosis. As an important component of the innate immune system, early activation of inflammasomes in a variety of immune cell subsets can mediate inflammatory response and immunological conditions after burn injury. Here, we review the current knowledge of inflammasomes and its role in immunological and inflammatory response at the early stage of burn injury.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Fisiología
/
Quemaduras
/
Citocinas
/
Apoptosis
/
Mediadores de Inflamación
/
Caspasa 1
/
Interleucina-18
/
Alergia e Inmunología
/
Interleucina-1beta
/
Inflamasomas
Límite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Burns
Año:
2014
Tipo del documento:
Article