Magnetic resonance-guided focused ultrasound surgery (MRgFUS) of uterine fibroids in Singapore
Annals of the Academy of Medicine, Singapore
;
: 550-558, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-312226
ABSTRACT
<p><b>INTRODUCTION</b>Uterine fibroids are the most common type of gynaecologic benign tumours, occurring in 25% to 50% of women during their reproductive lives. About half of the affected women have clinically significant symptoms, including abnormal bleeding, menstrual pain, frequent urination, constipation and abdominal distension. Magnetic resonance-guided focused ultrasound surgery (MRgFUS) has been used to treat patients with benign lesions and a variety of malignancies. The objective of this study is to evaluate symptom relief before and after MR-guided ultrasound ablation of fibroids.</p><p><b>MATERIALS AND METHODS</b>A total of 37 patients with symptomatic uterine fibroids were treated in this study.</p><p><b>RESULTS</b>MRgFUS treatment led to a significant, time-dependent decrease in not only Symptom Severity Scores (SSS), but also the mean fibroid volume. The average reductions in volume were 41.6% and 52.6% at 6 months and 12 months respectively (P <0.05). The mean SSS of the 37 patients was 41.7 ± 2.8 before treatment whereas the average SSS was 26.9 ± 3.6, 20.7 ± 3.4, 18.5 ± 3.6, 16.5 ± 7.1, 9.8 ± 3.6 at 3 months, 6 months, 1 year, 2 years, and 3 to 4 years respectively. The decrease in scores was significant at all time points up to 3 to 4 years (P <0.05 and P <0.001).</p><p><b>CONCLUSION</b>MRgFUS is a safe and effective non-invasive treatment for patients with symptomatic fibroids.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Singapur
/
Cirugía General
/
Neoplasias Uterinas
/
Imagen por Resonancia Magnética
/
Estudios Prospectivos
/
Resultado del Tratamiento
/
Ultrasonografía Intervencional
/
Cirugía Asistida por Computador
/
Diagnóstico
/
Leiomioma
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
Límite:
Adulto
/
Femenino
/
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Annals of the Academy of Medicine, Singapore
Año:
2014
Tipo del documento:
Artículo
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