Resting-state functional magnetic resonance imaging of first-onset major depressive disorder: analysis of 18 cases / 南方医科大学学报
Journal of Southern Medical University
; (12): 1277-1281, 2014.
Article
en Zh
| WPRIM
| ID: wpr-312589
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the changes in brain regional homogeneity in first-onset major depressive disorders (MDDs) using resting-state functional magnetic resonance imaging (fMRI).</p><p><b>METHODS</b>Eighteen patients with first-onset MDDs and twenty gender- and age-matched healthy controls underwent resting-state fMRI scans to compare the regional homogeneities of the brain regions.</p><p><b>RESULTS</b>Compared with the normal controls, the patients with MDDs showed significantly decreased regional homogeneity in the left posterior cingulated gyrus, bilateral inferior temporal gyrus, bilateral superior temporal gyrus, left inferior frontal gyrus, left hippocampa gyrus, left posterior central gyrus, left angular gyrus, right amygdala, right orbital frontal gyrus, right supplementary motor area, and right cerebellar lobe.</p><p><b>CONCLUSION</b>Patients with first-onset MDDs have dysfunctions in the brain regions closed related with cognition and emotional control.</p>
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Lóbulo Temporal
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Encéfalo
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Imagen por Resonancia Magnética
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Estudios de Casos y Controles
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Cerebelo
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Cognición
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Trastorno Depresivo Mayor
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Diagnóstico
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Emociones
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Lóbulo Frontal
Tipo de estudio:
Diagnostic_studies
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Observational_studies
Límite:
Humans
Idioma:
Zh
Revista:
Journal of Southern Medical University
Año:
2014
Tipo del documento:
Article