Antigen expression and the endothelization of biologic blood vessel matrix / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 51-53, 2004.
Artículo
en Chino
| WPRIM
| ID: wpr-312868
ABSTRACT
This study sought to explore the change of the major histocompatibility complex (MHC) antigen expression and the endothelization of blood vessel in minor pig after trypsin treatment, and to provide data for xenotransplantation and pig vessel for use in tissue engineering. Western blot assays were conducted for detecting the expression of MHC xenoantigens. Scanning electron microscopy was used for checking the endothelization of decellularized blood vessel. The results showed that MHC antigen is not expressed after trypsin treatment. The endothelization is accomplished. The endothelial cells have normal morphological distribution. These demonstrate that the antigen of pig aorta is significantly decreased and it can be used for constructing new vascular grafts.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Porcinos
/
Porcinos Enanos
/
Bioprótesis
/
Prótesis Vascular
/
Células Cultivadas
/
Biología Celular
/
Ingeniería de Tejidos
/
Células Endoteliales
/
Andamios del Tejido
Límite:
Animales
Idioma:
Chino
Revista:
Journal of Biomedical Engineering
Año:
2004
Tipo del documento:
Artículo
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