Study on a new antarthritic injection--O-carboxymethyl chitosan / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 25-27, 2004.
Artículo
en Chino
| WPRIM
| ID: wpr-312874
ABSTRACT
A type of water-soluble carboxymethyl chitosan (O--CMC), with 76% degree of substitution determined by conductivity method, was prepared by using chloroacetic acid to react with C6-OH of chitosan. The solubility of O--CMC was characterized also. Animal experiment in rabbits showed that O--CMC could lubricate arthron, inhibit proliferation of fibroblast cells on rabbits' knee joints, benefit the process of repairing pathologic articular cartilage, and produce good therapeutic effect on rheumatoid arthritis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Artritis Experimental
/
Cartílago Articular
/
Usos Terapéuticos
/
Quitosano
/
Proliferación Celular
/
Quimioterapia
/
Fibroblastos
/
Inyecciones Intraarticulares
/
Articulación de la Rodilla
Límite:
Animales
Idioma:
Chino
Revista:
Journal of Biomedical Engineering
Año:
2004
Tipo del documento:
Artículo
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