Prevalence and risk factors of retinopathy of prematurity / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 567-569, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-313731
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the prevalence and the risk factors of retinopathy of prematurity (ROP).</p><p><b>METHODS</b>Totally 172 premature infants who were less than 37 weeks postconceptional age, or more than 37 weeks but weighing < 2 500 g at birth, and born at PUMC hospital from May 1, 2003 to November 30, 2004, were enrolled in this study. Their fundus were routinely checked. Diagnosis and staging of ROP were performed according to the international guidelines. Another 20 mature infants were selected as the control group.</p><p><b>RESULTS</b>Twelve infants quitted the treatment or died. The remaining 160 infants completed the follow up. The prevalence of ROP in the premature group was 19.4%, while no ROP was found in the control group. The prevalence of ROP in subgroup with body weight < or = 2 000 g (28.4%) was significantly higher than in subgroup with body weight > 2 000 g (8.3%, chi2 = 10.217, P = 0.001) at birth. The prevalence of ROP in subgroup with postconceptional age < or = 32 weeks (42.5%) was significantly higher than in subgroup with postconceptional age > 32 weeks (11.7%, chi2 = 18.258, P = 0.000). The postconceptional age (OR = 0.959, P = 0.036) and body weight (OR = 0.999, P = 0.026) were the most important risk factors of ROP. Furthermore, blood transfusion ( OR = 0.076, P = 0.029) and Apgar score ( OR = 23.62, P = 0.012) were inversely correlated with ROP. Correlation was not found between ROP prevalence and oxygen inhalation mode, surface active substance, administration of dopamine and dexamethasone, and mother conditions.</p><p><b>CONCLUSIONS</b>The prevalence of ROP is higher in premature infants than in mature infants. Shorter postconceptional age and lower body weight may result in higher ROP incidence. Routine screening of fundus in premature infants may be helpful for the early detection of ROP.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Terapia por Inhalación de Oxígeno
/
Puntaje de Apgar
/
Retinopatía de la Prematuridad
/
Recién Nacido de Bajo Peso
/
Recien Nacido Prematuro
/
China
/
Epidemiología
/
Prevalencia
/
Factores de Riesgo
/
Edad Gestacional
Tipo de estudio:
Estudio de etiología
/
Guía de Práctica Clínica
/
Estudio de prevalencia
/
Factores de riesgo
/
Estudio de tamizaje
Límite:
Femenino
/
Humanos
/
Masculino
/
Recién Nacido
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Acta Academiae Medicinae Sinicae
Año:
2006
Tipo del documento:
Artículo
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