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Research progress of tumor microenvironment and non-Hodgkin's lymphomas / 中国实验血液学杂志
Journal of Experimental Hematology ; (6): 843-847, 2011.
Artículo en Chino | WPRIM | ID: wpr-313881
ABSTRACT
Non-Hodgkin's lymphoma cells including lymphoma stem cells reside in a specific microenvironment in which a series of nonmalignant bystander cells and cytokines play a crucial role in the genesis and development of non-Hodgkin's lymphomas. In addition, tumor microenvironment has important prognostic significance in Non-Hodgkin's lymphomas. Blocking the cross-talk between the tumor microenvironment and lymphoma cells may thus represent a promising new strategy for treating Non-Hodgkin's lymphomas. This review summarizes the current advance in studies of the tumor microenvironment and non-Hodgkin's lymphomas, including cells in tumor microenvironment, role of mesenchymal stem cells and stromal cells, auxiliary role of T cell subsets, macrcphage and dentritic cells, cytokines, immune surveillance and so on.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Células Dendríticas / Linfoma no Hodgkin / Citocinas / Subgrupos de Linfocitos T / Alergia e Inmunología / Microambiente Tumoral / Macrófagos Límite: Humanos Idioma: Chino Revista: Journal of Experimental Hematology Año: 2011 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Células Dendríticas / Linfoma no Hodgkin / Citocinas / Subgrupos de Linfocitos T / Alergia e Inmunología / Microambiente Tumoral / Macrófagos Límite: Humanos Idioma: Chino Revista: Journal of Experimental Hematology Año: 2011 Tipo del documento: Artículo