Clinical observation on treatment of chronic aplastic anemia by Shengxuening and cyclosporin A / 中国结合医学杂志
Chinese journal of integrative medicine
;
(12): 142-145, 2006.
Artículo
en Inglés
| WPRIM
| ID: wpr-314070
ABSTRACT
<p><b>OBJECTIVE</b>To explore the therapy to further elevate the efficacy of the treatment of chronic aplastic anemia (CAA).</p><p><b>METHODS</b>Forty-five patients with CCA were assigned into two groups, the 26 patients in the treated group were treated by Shengxuening (a Chinese herbal preparation) and cyclosporin A (CsA), and the 19 patients in the control group were treated with androgen alone, with the therapeutic course lasting for over 3 months. Changes of peripheral blood picture, and the colony productivity of burst forming unit-erythroid (BFU-E), colony forming unit-erythroid (CFU-E) and colony forming unit-granulocyte macrophage (CFU-GM) in bone marrow were observed before and after 3 months treatment. The amount of erythrocyte and platelet infusion, frequency of infection, condition of hemorrhage and relevant death were also observed. The follow-up study was conducted for over half a year.</p><p><b>RESULTS</b>The total effective rate in the treated group was 84.6%, which was significantly higher than that in the control group (52.6%, P < 0.05). Levels of hemoglobin, reticulocyte, neutrophil and platelet increased after treatment in the treated group, as compared with those before treatment, with significant difference (P < 0.05), and the colony productivity of BFU-E, CFU-E and CFU-GM in bone marrow also got significantly increased (P < 0.01), and showed significant difference from those in the control group (P < 0.05).</p><p><b>CONCLUSION</b>Shengxuening-assisting CsA therapy is an effective measure for treatment of CAA.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Recuento de Plaquetas
/
Reticulocitos
/
Estanozolol
/
Comprimidos
/
Hemoglobinas
/
Medicamentos Herbarios Chinos
/
Células Precursoras Eritroides
/
Enfermedad Crónica
/
Estudios de Seguimiento
/
Ciclosporina
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
Límite:
Adulto
/
Anciano
/
Humanos
Idioma:
Inglés
Revista:
Chinese journal of integrative medicine
Año:
2006
Tipo del documento:
Artículo
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