Study on fast screening antifungus activity of endophytes from Pseudolarix kaempferi / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To screen antifungal activity of endophytes from Pseudolarix kaempferi.</p><p><b>METHOD</b>Endophytes from P. kaempferi were separated. By means of microdilution method, antifungal active endophytes were fast screened by Pyricularia oryzae P-2b model, and activity of endophytes against pathogenic fungus was studied.</p><p><b>RESULT</b>44.8% of endophytes showed activity against P. oryzae P-2b in Pseudolarix kaempferi. Among them JJ314, JJ323 introduced formation of characteristic beads and swellings on the growing hyphae, JJ324 inhibited the conidia germination. They all showed activity against Trichophyton rubrum, Cryptococcus neoformans and Candida albicans.</p><p><b>CONCLUSION</b>Endophytes from P. kaempferi are a potential resource for the development of antifungal agent.</p>