Study on influence of processing methods on chemical constituents in Radix Paeoniae Alba / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1418-1421, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-316035
ABSTRACT
<p><b>OBJECTIVE</b>The influence of processing methods on chemical constituents in Radix Paeoniae Alba was observed.</p><p><b>METHOD</b>A HPLC method was used for analyzing the changes of eight major constituents, namely gallic acid, paeoniflorin sulfonate, catechin, paeoniflorin sulfonate, albiflorin, paeoniflorin, benzoic acid, pentagalloylglucose and benzoylpaeoniflorin, with the three processing procedures of decorticating, boiling and fumigating by burning of sulphur. Analysis was performed using a Zorbax SB-C18 column (4.6 mm x 250 mm, 5 microm) with the mixture of acetonitrile (A) and 0.015% phosphoric acid solution as mobile phase in gradient mode. The detection wavelength was set at 230 nm and the column temperature was at 30 degrees C.</p><p><b>RESULT</b>Except for gallic acid and pentagalloylglucose, the other constituents decreased during procedure of decorticating and boiling. Fumigating by burning of sulphur would produce a new compound, paeoniflorin sulfonate, which was a byproduct from the reaction of paeoniflorin with SO2.</p><p><b>CONCLUSION</b>The significant changes were produced in chemical constituents of Radix Paeoniae Alba during three processing procedures. Therefore, the processing of Radix Paeoniae Alba should be strictly controlled and standardized.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Plantas Medicinales
/
Azufre
/
Benzoatos
/
Hidrocarburos Aromáticos con Puentes
/
Estructura Molecular
/
Química
/
Cromatografía Líquida de Alta Presión
/
Tecnología Farmacéutica
/
Raíces de Plantas
/
Paeonia
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2006
Tipo del documento:
Artículo
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