WHO Classification of Malignant Lymphomas in Korea: Report of the Third Nationwide Study
Korean Journal of Pathology
; : 254-260, 2011.
Article
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| WPRIM
| ID: wpr-31611
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND: The aim of study was to determine the relative frequency of malignant lymphoma according to World Health Organization (WHO) classification in Korea. METHODS: A total of 3,998 cases diagnosed at 31 institutes between 2005 and 2006 were enrolled. Information including age, gender, pathologic diagnosis, site of involvement and immunophenotypes were obtained. RESULTS: The relative frequency of non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL) was 95.4% and 4.6%, respectively. B-cell lymphomas accounted for 77.6% of all NHL, while T/natural killer (T/NK)-cell lymphomas accounted for 22.4%. The most frequent subtypes of NHL were diffuse large B-cell lymphoma (42.7%), extranodal marginal zone B-cell lymphoma (MZBCL) of mucosa-associated lymphoid tissue (19.0%), NK/T-cell lymphoma (6.3%) and peripheral T-cell lymphoma (PTCL), unspecified (6.3%), in decreasing order. The relative frequency of HL was nodular sclerosis (47.4%), mixed cellularity (30.6%), and nodular lymphocyte predominant (12.1%) subtypes. Compared with a previous study in 1998, increase in gastric MZBCL and nodular sclerosis HL, and slight decrease of follicular lymphoma, PTCL, and NK/T-cell lymphoma were observed. CONCLUSIONS: Korea had lower rates of HL and follicular lymphoma, and higher rates of extranodal NHL, extranodal MZBCL, and NK/T-cell lymphoma of nasal type compared with Western countries. Changes in the relative frequency of lymphoma subtypes are likely ascribed to refined diagnostic criteria and a change in national health care policy.
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Índice:
WPRIM
Asunto principal:
Esclerosis
/
Organización Mundial de la Salud
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Linfoma no Hodgkin
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Enfermedad de Hodgkin
/
Linfocitos
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Linfoma de Células B
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Linfoma de Células T Periférico
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Linfoma Folicular
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Linfoma de Células B de la Zona Marginal
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Atención a la Salud
País/Región como asunto:
Asia
Idioma:
En
Revista:
Korean Journal of Pathology
Año:
2011
Tipo del documento:
Article