Analysis of neutralized antibody level of the poliomyelitis in healthy population in Fujian province / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To understand the neutralized antibody level of the poliomyelitis among healthy people and provide scientific evidence for the immunization strategy since routine and intensified immunization with oral polio vaccine (OPV) in Fujian province.</p><p><b>METHODS</b>The poliomyelitis antibody level of healthy people were detected by neutralization test of the micro cells.</p><p><b>RESULTS</b>The neutralizing antibody positive rates were 99.0%, 99.3%, 97.5% and GMTs were 1:79.1, 1:31.2, 1:24.7 for polio I, II, III respectively in 400 serum specimens from 1-59 years old. GMTs present a trend of decreasing as age's increasing.</p><p><b>CONCLUSION</b>A protective barrier had been built against poliomyelitis in healthy people in Fujian province through routine and intensified immunization with OPV.</p>