Estrogen Receptor Gene PvuII and XbaI Polymorphism in Patients with Endometriosis / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 1531-1536, 2003.
Artículo
en Coreano
| WPRIM
| ID: wpr-31769
ABSTRACT
OBJECTIVE:
To explore the association of the estrogen receptor PvuII and XbaI polymorphism with endometriosis.METHODS:
One hundred sixty women with surgically or histologically diagnosed endometriosis of stages I-IV, and 142 patients with no evidence of endometriosis by laparoscopy or laparotomy served as control. Frequency and distribution of PvuII and XbaI polymorphisms for estrogen receptor gene were evaluated.RESULTS:
There was no statistically significant difference in the allele distribution of PvuII polymorphism between the patients and the controls (pp of 35%, pP of 51%, PP of 14% vs. 42%, 44%, 15%, p>0.1); or in the frequency of the positive PvuII allele (0.61 vs. 0.63, p>0.1). And no significant difference was also observed in the allele distribution of XbaI polymorphism between the patients and the controls (xx of 66%, xX of 29%, XX of 5% vs. 68%, 30%, 1%, p>0.1); or in the frequency of the positive XbaI allele (0.80 vs. 0.83, p>0.1).CONCLUSION:
These results suggest that the PvuII or XbaI polymorphism of the estrogen receptor gene is not associated with the risk for endometriosis in the Korean population.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Laparoscopía
/
Endometriosis
/
Alelos
/
Estrógenos
/
Laparotomía
Límite:
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Obstetrics and Gynecology
Año:
2003
Tipo del documento:
Artículo
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