Leukemia stem cells and their microenvironment--editorial / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1139-1141, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-318772
ABSTRACT
As pioneer of tumor stem cell research, leukemia stem cell research has not only important theoretical significance, but also clinical application potential. The survival and development of stem cells are directly impacted by their microenvironment. The research on leukemia stem cells and their microenvironment are now becoming a hot topic. The author presumes that stem cells are a population with heterogenecity and hierarchy; any single cell from the population is difficult to form a clone; the interaction between the leukemia stem cell and its microenvironment can be described by the concept of leukemia stem cell niche. In this article, the leukemia cell population with heterogenecity and hierarchy as well as leukemia stem cell niche were summarized and discussed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Células Madre Neoplásicas
/
Leucemia
/
Células del Estroma
/
Biología Celular
/
Línea Celular Tumoral
/
Alergia e Inmunología
/
Nicho de Células Madre
/
Genética
/
Metabolismo
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Experimental Hematology
Año:
2007
Tipo del documento:
Artículo
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