Flow cytometry analysis and differentiation study of selected nestin positive cells / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To verify the hypothesis that selected nestin positive cells derived from human fetal pancreas (according as medical ethnics) have surface markers similar to bone marrow mesenchymal stem cells (MSCs), and that these cells have multilineage potential.</p><p><b>METHOD</b>The cell surface markers were determined by flow cytometry, and then the potential that these cells might be differentiated into adipocytes and osteoplasts were explored.</p><p><b>RESULT</b>These cells have similar surface markers as MSCs of bone marrow origin. These cells was induced to differentiate into adipocytes and osteoplasts.</p><p><b>CONCLUSION</b>Selected nestin positive cells derived from human fetal pancreas have certain characteristics of MSCs.</p>