Expression of testosterone in the rapid growing rat condylar cartilage and the expression changes after the function mandibular advancement / 华西口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the expressions of Testosterone in the condylar cartilage of rapid growing rats.</p><p><b>METHODS</b>The mimic functional appliances were used in experiment groups and rats were killed after 3 days, 1 week, 2 weeks, 3 weeks and 4 weeks. Immunohistochemical technique was used to detect the expression of T.</p><p><b>RESULTS</b>T was expressed throughout the condylar cartilage. The Highest expressions were in mature layers of both experiment and control groups. Along with the maturation, the expressions of T in the condylar cartilage were changed respectively, and the immunostain levels in the mature layer of experiment groups 2 and 3 weeks were higher than those of control groups (P < 0.05).</p><p><b>CONCLUSION</b>1. T is a member of cartilage growth and development control system. 2. The orthopedic mechanism of functional appliance may be conducted by T.</p>