Toll-like receptors and their role in pathogenesis and vaccine study of cutaneous diseases / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 222-229, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-319805
ABSTRACT
Toll like receptor (TLR) can specifically recgnize pathogen-associated molecular patterns (PAMPs) and is considered as an important link between innate and adaptive immunity. It has been shown that TLR plays an important role in the pathogenesis and pathophysiology of a variety of skin diseases. Moreover, TLR agonists have exhibited promising therapeutic effects on the disease models and are expected to be novel vaccine adjuvants. Investigations of the underlying mechanism will give new insights into these diseases. This review will discuss the relationship between TLR and pathogenesis and management of some cutaneous diseases.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Enfermedades de la Piel
/
Transducción de Señal
/
Alergia e Inmunología
/
Receptores Toll-Like
/
Inmunidad Adaptativa
/
Inmunidad Innata
/
Metabolismo
Tipo de estudio:
Estudio de etiología
Idioma:
Chino
Revista:
Journal of Zhejiang University. Medical sciences
Año:
2011
Tipo del documento:
Artículo
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