Change of zero-stress state of portal vein in the rat during the pathogenesis of intrahepatic portal hypertension / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 753-755, 2006.
Article
en Zh
| WPRIM
| ID: wpr-320491
Biblioteca responsable:
WPRO
ABSTRACT
A model of intrahepatic portal hypertension was established in SD rats by injection of carbon tetrachloride (CCl4). By observing the opening angle of the portal vein, the zero-stress state of the portal veins was studied at different time during the pathogenesis of intrahepatic portal hypertension. After CCl4 injection, the opening angles of the portal veins were increased, in the tenth week, they were much greater than those in the corresponding controls (P<0.05). The results suggest that during the pathogenesis of portal hypertension, unequal remodeling exists in the portal veins to change its biomechanical properties, and the residual stress and strain of the portal veins in portal hypertensive rats are greater than those in normal controls.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Vena Porta
/
Estrés Mecánico
/
Intoxicación por Tetracloruro de Carbono
/
Ratas Sprague-Dawley
/
Modelos Animales de Enfermedad
/
Hipertensión Portal
/
Inyecciones Subcutáneas
Tipo de estudio:
Etiology_studies
Límite:
Animals
Idioma:
Zh
Revista:
Journal of Biomedical Engineering
Año:
2006
Tipo del documento:
Article