Collision tumor of the kidney composed of clear cell carcinoma and collecting duct carcinoma: report of a case with unusual morphology and clinical follow-up / 癌症
Chinese Journal of Cancer
; (12): 351-355, 2014.
Article
en En
| WPRIM
| ID: wpr-320528
Biblioteca responsable:
WPRO
ABSTRACT
We report the case of a 67-year-old female who presented with a large renal mass. Gross examination of the nephrectomy specimen demonstrated a 6-cm renal mass that invaded into the renal sinus and perinephric fat. Histologic examination revealed two distinct tumor types. The first type was a conventional (clear cell) renal cell carcinoma that was of low nuclear grade and comprised the minority of the overall tumor. The second type was a high-grade collecting duct carcinoma with glandular/tubular differentiation and composed the majority of the tumor. Immunohistochemical studies demonstrated distinctive patterns of the two tumor types, thus confirming two distinct lineages. Five months postoperatively, the patient developed metastasis to the lungs and right hilar lymph node region. A fine needle aspiration of a lung nodule demonstrated a metastatic, poorly differentiated carcinoma, similar to the collecting duct carcinoma component in the kidney. Collision tumors of the kidney are rare with fewer than 10 cases reported in the literature. Our report further expands the spectrum of this rare phenomenon.
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Índice:
WPRIM
Asunto principal:
Patología
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Carcinoma de Células Renales
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Estudios de Seguimiento
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Tumor Mixto Maligno
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Biopsia con Aguja Fina
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Neoplasias Renales
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Neoplasias Pulmonares
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Linfoma
Tipo de estudio:
Observational_studies
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Prognostic_studies
Límite:
Aged
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Female
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Humans
Idioma:
En
Revista:
Chinese Journal of Cancer
Año:
2014
Tipo del documento:
Article