Rescue of Heart Failure by Mitochondrial Recovery / 대한배뇨장애요실금학회지
International Neurourology Journal
;
: 5-12, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-32097
ABSTRACT
Heart failure (HF) is a multifactorial disease brought about by numerous, and oftentimes complex, etiological mechanisms. Although well studied, HF continues to affect millions of people worldwide and current treatments can only prevent further progression of HF. Mitochondria undoubtedly play an important role in the progression of HF, and numerous studies have highlighted mitochondrial components that contribute to HF. This review presents an overview of the role of mitochondrial biogenesis, mitochondrial oxidative stress, and mitochondrial permeability transition pore in HF, discusses ongoing studies that attempt to address the disease through mitochondrial targeting, and provides an insight on how these studies can affect future research on HF treatment.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Permeabilidad
/
Biogénesis de Organelos
/
Procesamiento Proteico-Postraduccional
/
Estrés Oxidativo
/
Corazón
/
Insuficiencia Cardíaca
/
Mitocondrias
Idioma:
Inglés
Revista:
International Neurourology Journal
Año:
2016
Tipo del documento:
Artículo
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