Incidence of human herpes virus 1-4 type in saliva of 245 human immunodeficiency virus-infected patients / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 514-517, 2012.
Artículo
en Chino
| WPRIM
| ID: wpr-322347
ABSTRACT
<p><b>OBJECTIVE</b>To determine the incidence of human herpes virus (HHV) 1-4 type including herpes simplex virus type-1 (HSV-1), herpes simplex virus type-2 (HSV-2), varicella-zoster virus (VZV), Epstein-Barr virus(EBV) in the saliva of human immunodeficiency virus (HIV) -infected patients.</p><p><b>METHODS</b>The incidence of salivary HSV-1, HSV-2, VZV and EBV from 245 HIV-seropositive individuals and control group was used to investigate by polymerase chain reaction(PCR) or nested PCR. The data was analyzed by SPSS 18.0 statistical software.</p><p><b>RESULTS</b>In the 245 HIV-seropositive individuals, the detection rates of HSV-1, HSV-2, VZV, EBV were 29.0%, 3.3%, 4.1%, 82.0%. In the control group, the detection rates of HSV-1, HSV-2, VZV, EBV were 13.3%, 0, 0, 36.7%. Four HHVs were significantly more prevalent in the salivas of HIV-seropositive persons than those in the control group (P < 0.01). The detection rates of HSV-1, HSV-2, VZV and EBV DNA were no difference between the HIV-positive group with highly active antiretroviral therapy (HAART) and HIV-positive group without HAART (P > 0.05).</p><p><b>CONCLUSION</b>There is a high prevalence of HHV infection in HIV-infected people in Yunnan. The most common virus are EBV, followed by HSV-1, but VZV and HSV-2 are rarely detected. HHV co-infection is also observed.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Saliva
/
ADN Viral
/
Infecciones por VIH
/
China
/
Reacción en Cadena de la Polimerasa
/
Incidencia
/
Prevalencia
/
Herpesvirus Humano 3
Tipo de estudio:
Estudio de incidencia
/
Estudio de prevalencia
/
Estudio pronóstico
Límite:
Adulto
/
Humanos
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
West China Journal of Stomatology
Año:
2012
Tipo del documento:
Artículo
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