Experimental study of corpus cavernosal nerve evoked potential in diabetic rats / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVES</b>To observe the cavernosal nerve dysfunction of diabetic Sprague Dawley rats.</p><p><b>METHODS</b>Thirty-five Sprague-Dawley rats were divided randomly into diabetes model group(n = 25) and normal group(n = 10). Diabetes model was established by administration of streptozotocin (63 mg/kg) in single intraperitoneal dosing. Giving single wave stimulus, corpus cavernosal nerve was measured for its latent period of reaction and myopotential.</p><p><b>RESULTS</b>Compared with other groups, diabetic rats had longer reflection latent period(P < 0.01) and higher corpus cavernosum smooth muscle myopotential (P < 0.01).</p><p><b>CONCLUSIONS</b>The results indicate that corpus cavernosal nerve dysfunction may play an important role in the erectile dysfunction of diabetic rats.</p>