The role of transforming growth factor beta superfamily in male germ cell development / 中华男科学杂志
National Journal of Andrology
;
(12): 435-437, 2002.
Artículo
en Chino
| WPRIM
| ID: wpr-322569
ABSTRACT
Transforming growth factor beta (TGF beta) superfamily can regulate the development of primordial germ cell (PGC) and gonocyte. TGF beta, bone morphogenetic protein (BMP), activin, inhibin, and anti-Müllerian hormone (AMH), all of which belong to the TGF beta superfamily, can play important roles in male germ cell development. Their downstream signaling molecules, Smads proteins are involved in the signal transduction pathway. In addition, TGF beta and AMH contribute to the apoptosis during development. Understanding this effect will help to elucidate the molecular mechanism of the early development of male reproductive system and the pathogenesis of testicular cancer.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Espermatogénesis
/
Espermatozoides
/
Hormonas Testiculares
/
Glicoproteínas
/
Factor de Crecimiento Transformador beta
/
Proteínas Morfogenéticas Óseas
/
Activinas
/
Hormona Antimülleriana
/
Inhibidores de Crecimiento
Límite:
Animales
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
National Journal of Andrology
Año:
2002
Tipo del documento:
Artículo
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