The establishment of testicular fibrosis model in Wistar rats / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVES</b>To establish the testicular fibrosis model in rats.</p><p><b>METHODS</b>Wistar rats were divided into control group(n = 12) and model group(n = 40) randomly. Testicular fibrosis model was built with the classical method of establishing experimental autoimmune orchitis (EAO) combined with injecting Bacille Calmette-Guerin (BCG) into left testis.</p><p><b>RESULTS</b>The incidence rate of EAO and the rate of testicular fibrosis were 100%, 11.1% and 100%, 81.5% at 80, 140 days after the first infection, respectively.</p><p><b>CONCLUSIONS</b>The model of rat testicular fibrosis was established successfully.</p>