Study on semi-synthetic transforming technology for the natural product of isocorydione / 药学学报
Acta Pharmaceutica Sinica
; (12): 1471-1475, 2011.
Article
en Zh
| WPRIM
| ID: wpr-323099
Biblioteca responsable:
WPRO
ABSTRACT
Transforming technology for semi-synthesized isocorydione from the natural product ofisocorydine was studied. The factors affecting on the reaction yield were investigated. UV spectrophotometry was used to indicate the semi-synthesized yield of isocorydione. The optimum reaction conditions were determined as following: reacting for 12 h in the solution of sodium dihydrogen phosphate at pH 10, the temperature was 25 degrees C and the ratio of isocorydine to Fremy's radical was 1 : 2. Under the optimum conditions, the yield could reach up to 50.0%. The molecular structure of isocorydione was elucidated by X-ray single-crystal diffraction analysis for the first time.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Oxidación-Reducción
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Aporfinas
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Plantas Medicinales
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Espectrofotometría Ultravioleta
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Temperatura
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Difracción de Rayos X
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Estructura Molecular
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Química
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Cristalografía por Rayos X
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Papaveraceae
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Año:
2011
Tipo del documento:
Article