Experience of transcather closure in patients with postinfarction ventricular septal defects / 中华心血管病杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the therapeutic effect of transcather closure in patients with postinfarction ventricular septal defects (VSD).</p><p><b>METHODS</b>Transcatheter VSD closure was performed in 12 patients with postinfarction VSD (10 muscular and 2 membranes defects) on top of standard pharmacotherapy and percutaneous transluminal coronary angioplasty (PTCA) as indicated.</p><p><b>RESULTS</b>(1) Percutaneous interventional VSD closure was successful in 9 out 12 patients (75%) and these 9 patients survived post procedure. (2) The medial time between VSD occurrence and closure was (15.5 +/- 9.2) days. Procedure-related complications such as device embolization and malignant arrhythmia occurred in 3 patients (25%). The medial time between procedure and discharge from hospital was (11.3 +/- 5.2) days. (3) Coronary angiography was performed in 2 patients and 4 stents were implanted in diseased lesions.</p><p><b>CONCLUSION</b>Transcatheter closure could be successfully performed in selected patients with postinfarction VSD.</p>