Separation and purification of alkaloids from radix of Zanthoxylum nitidum by macroporous adsorption resin / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To obtain the optimal conditions for separating the alkaloids from the extract of Radix of Zanthoxylum nitidum by selecting appropriate macroporous adsorption resins.</p><p><b>METHOD</b>Eight types of macroporous adsorption were evaluated in separating efficiency with measuring the adsorption ratio and eluting ratio of Alkaloids as indexes.</p><p><b>RESULT</b>The XDA-5 macroporous adsorption resin had the best separating efficiency. After enrichment and purification with it, the product purity and yield of alkaloids were up to 33.25% and 90.15%, respectively.</p><p><b>CONCLUSION</b>This method is simple, feasible and fit for industry production.</p>