The relationship between hypertension and cerebral hemodynamic scores of vascular function accumulative / 中华流行病学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To probe into the relationship between hypertension and hemodynamic score of cerebral vascular accumulative function by though studying the history of hypertension and level of blood pressure.</p><p><b>METHODS</b>The database of blood pressure and cerebral vascular hemodynamic indexes (CVHI) were from baseline data and measurement in a cohort. 18,512 participants who met the included criteria were enlisted in the study. The function scores were estimated using uniform methods according to CVHI. Participants were grouped by age, years of having hypertension and level of blood pressure. Differences of the function score between different groups were compared.</p><p><b>RESULTS</b>The function score in hypertension group was significantly lower than that of normal tension group, which decreased by 13.3 points. Within 5 years of hypertension history, the function score decreased as course of hypertension prolonged. The same trend was found between the score and level of both systolic and diastolic blood pressure. When systolic blood pressure elevated to 140 mmHg or diastolic blood pressure elevated to 95 mmHg, the function score was below 75 points.</p><p><b>CONCLUSION</b>There were significant relationship between decrease of the function scores and medical history, course of hypertension as well as level of blood pressure.</p>