Your browser doesn't support javascript.
loading
A case-control study on the risk factors of Alzheimer's disease in military elderly men / 中华流行病学杂志
Chinese Journal of Epidemiology ; (12): 890-893, 2004.
Artículo en Chino | WPRIM | ID: wpr-325007
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the risk of Alzheimer's disease (AD) associated with life style, early exposure to magnetic fields, family history of dementia and other risk factors.</p><p><b>METHODS</b>We conducted a case-control study among the inpatients of Chinese PLA General Hospital in 2000 - 2003. Sixty-two AD cases and 124 controls were selected and matched for age. Univariate and multivariate analyses were conducted using logistic regression model.</p><p><b>RESULTS</b>All subjects were males aged 66 to 102. In univariate analysis, lack of social activities, more physical exercises, early exposure to magnetic fields, suffering from negative life events and family history of dementia were statistically different between two groups (P < 0.05). Multivariate analysis showed that after adjusting for potential confounders, suffering from negative life events, family histories of dementia increased the risk of AD with odds ratio (OR) and 95% confidence interval (CI) 3.27 (1.53 - 6.97) and 5.78 (1.39 - 24.10). Early exposure to magnetic fields seemed a possible risk factor for AD, with OR (95% CI) 2.49 (0.96 - 6.45). The amount of social activities, cigarette smoking and history of cancers were negatively correlated with AD and their ORs (95% CI) were 0.81 (0.72 - 0.92), 0.46 (0.21 - 1.00) and 0.31 (0.12 - 0.82) respectively.</p><p><b>CONCLUSION</b>The study demonstrated that suffering from negative life events and family history of dementia were risk factors for AD, and the early exposure to magnetic fields might also play a role.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Fumar / Estudios de Casos y Controles / Modelos Logísticos / China / Epidemiología / Factores de Riesgo / Exposición Profesional / Campos Electromagnéticos / Enfermedad de Alzheimer / Personal Militar Tipo de estudio: Estudio de etiología / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Anciano / Aged80 / Humanos / Masculino País/Región como asunto: Asia Idioma: Chino Revista: Chinese Journal of Epidemiology Año: 2004 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Fumar / Estudios de Casos y Controles / Modelos Logísticos / China / Epidemiología / Factores de Riesgo / Exposición Profesional / Campos Electromagnéticos / Enfermedad de Alzheimer / Personal Militar Tipo de estudio: Estudio de etiología / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Anciano / Aged80 / Humanos / Masculino País/Región como asunto: Asia Idioma: Chino Revista: Chinese Journal of Epidemiology Año: 2004 Tipo del documento: Artículo