Evaluation of surgical resection of pulmonary metastasis of trophoblastic tumour / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 418-421, 2003.
Artículo
en Chino
| WPRIM
| ID: wpr-327068
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the role of lung lobectomy in the patients of tumor with lung metastases.</p><p><b>METHODS</b>A total of 45 cases of trophoblastic tumor with pulmonary metastases treated by lung lobectomy from 1985-2002 at PUMC hospital was retrospectively analyzed. Seven cases were diagnosed as invasive mole and thirty-eight as choriocarcinoma.</p><p><b>RESULTS</b>Lung lobectomy was performed in all of these patients after several courses of chemotherapy. Seven cases of invasive mole reached complete remission. Eleven cases of choriocarcinoma with stage IIIa had received average 13 courses of chemotherapy, 10 of them reached complete remission. Seventeen cases of choriocarcinoma with stage IIIb had received average 14.3 courses of chemotherapy, 11 of them reached complete remission. Ten cases of choriocarcinoma with stage IV had received average 15 courses of chemotherapy, six of them reached complete remission. In the 45 patients, histologic examination disclosed haemorrhagic necrotic tissue in 27 patients, 17 of them reached complete remission (63%). Histologic examination also revealed fibrosis around the focus in 16 patients, 14 of them reached complete remission (88%). Tuberculosis was found in 2 patients.</p><p><b>CONCLUSIONS</b>Although the development of effective chemotherapy has resulted in improved survival of patients with gestational trophoblastic tumor, lung lobectomy remains an important adjunct treatment in a selected subset of patients. Pathological examinations can help to estimate the prognosis.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Neumonectomía
/
Pronóstico
/
Cirugía General
/
Neoplasias Uterinas
/
Vincristina
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Coriocarcinoma
/
Metotrexato
/
Estudios Retrospectivos
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Adolescente
/
Adulto
/
Femenino
/
Humanos
/
Masculino
/
Embarazo
Idioma:
Chino
Revista:
Acta Academiae Medicinae Sinicae
Año:
2003
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS