Synthesis and the drug release properties of poly(acrylamide-co-glycosylallylamide) hydrogels / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 960-963, 2004.
Artículo
en Chino
| WPRIM
| ID: wpr-327170
ABSTRACT
Sugar-containing monomer glycosylallylamide (AAG) was synthesized by allyl amine and delta-gluconolactone in dimethylformamide (DMF) solution. The sugar-based hydrogels were prepared by free radical crosslinking copolymerization of AAG and acrylamide (AM). The release properties of Aspirin from xerogels matrices were studied and the release mechanism of Aspirin was further identified by evaluating the n value in Peppas equation. The results indicate that the drug release decreases with the increase of the sugar content of hydrogel.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Polímeros
/
Farmacocinética
/
Química
/
Aspirina
/
Acrilamida
/
Hidrogeles
/
Preparaciones de Acción Retardada
/
Gluconatos
/
Lactonas
Idioma:
Chino
Revista:
Journal of Biomedical Engineering
Año:
2004
Tipo del documento:
Artículo
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