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A study on the inhibiting effects of transforming growth factor-beta R II antibody on fibroblasts / 中华整形外科杂志
Article en Zh | WPRIM | ID: wpr-327305
Biblioteca responsable: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the inhibiting action of transforming growth factor-beta type R II receptor(TGF-beta R II) antibody to fibroblasts.</p><p><b>METHODS</b>Four groups of cultured skin fibroblasts were treated with different dosages of TGF-beta R II antibody. Examinations were performed with HYP, MTT, microscope, and flow cytometry techniques.</p><p><b>RESULTS</b>TGF-beta R II antibody resulted in significant inhibition of fibroblasts(P < 0.01).</p><p><b>CONCLUSION</b>TGF-beta R II antibody has inhibiting effects on the proliferation of skin fibroblasts and with a dose-dependent manner.</p>
Asunto(s)
Texto completo: 1 Índice: WPRIM Asunto principal: Farmacología / Microscopía Electrónica / División Celular / Células Cultivadas / Proteínas Serina-Treonina Quinasas / Receptores de Factores de Crecimiento Transformadores beta / Biología Celular / Alergia e Inmunología / Fibroblastos / Citometría de Flujo Límite: Adolescent / Child / Humans Idioma: Zh Revista: Chinese Journal of Plastic Surgery Año: 2003 Tipo del documento: Article
Texto completo: 1 Índice: WPRIM Asunto principal: Farmacología / Microscopía Electrónica / División Celular / Células Cultivadas / Proteínas Serina-Treonina Quinasas / Receptores de Factores de Crecimiento Transformadores beta / Biología Celular / Alergia e Inmunología / Fibroblastos / Citometría de Flujo Límite: Adolescent / Child / Humans Idioma: Zh Revista: Chinese Journal of Plastic Surgery Año: 2003 Tipo del documento: Article