Determination of the content of residual solvents in Haikesu I by head-space gas chromatography / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 599-601, 2014.
Article
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| WPRIM
| ID: wpr-329778
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WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the usefulness of head-space gas chromatography for the determination of methanol and ethanol in Haikesu I,a raw material of artificial musk.</p><p><b>METHODS</b>The determination was performed on HP-5(30 m×0.53 mm,5 Μm)capillary column with an hydrogen flame ionization detector. The solvent was dimethyl sulfoxide and the internal standard was acetone. The injector temperature and the detector temperature were controlled at 180 ℃ and 250 ℃,respectively. The carrier gas was nitrogen. The containers of head-space injector were preheated at 90 ℃ for 15 minutes. The column temperature was programmed raised,which achieved baseline separation of the components.</p><p><b>RESULTS</b>The results showed a good linear relationship for methanol and ethanol in their linearity range;and the limit of detection was 0.8 and 1.0 Μg/ml,respectively. The precision and average recoveries were satisfactory.</p><p><b>CONCLUSION</b>The head-space gas chromatography is simple,rapid,and precise technique for the measurement of residual solvents in Haikesu I.</p>
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Asunto principal:
Acetona
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Solventes
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Medicamentos Herbarios Chinos
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Química
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Cromatografía de Gases
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Etanol
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Metanol
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Ionización de Llama
Idioma:
En
Revista:
Acta Academiae Medicinae Sinicae
Año:
2014
Tipo del documento:
Article