A voxel-based morphometry study of grey matter volume changes in neuromyelitis optica patients / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 432-438, 2014.
Artículo
en Chino
| WPRIM
| ID: wpr-329808
ABSTRACT
<p><b>OBJECTIVE</b>To explore the grey matter volume (GMV) changes in neuromyelitis optica (NMO) patients using a voxel-based morphometry method.</p><p><b>METHODS</b>Whole brain structural images were acquired in 16 NMO patients and 16 gender-and age-matched healthy controls. Comparison of GMV between the two groups was analyzed by VBM8 toolbox of statistical parametric mapping 8.</p><p><b>RESULT</b>Compared with the controls, NMO patients showed decreased GMV in the frontal lobe, parietal lobe, temporal lobe, occipital lobe, limbic lobe, optic tract, caudate nucleus, thalamus, and cerebellum (all P < 0.005).</p><p><b>CONCLUSIONS</b>Regional atrophy of grey matter is found in NMO patients. Voxel-based morphometry can reveal brain volume changes sensitively.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Imagen por Resonancia Magnética
/
Estudios de Casos y Controles
/
Neuromielitis Óptica
/
Sustancia Gris
Tipo de estudio:
Estudio observacional
Límite:
Adolescente
/
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Acta Academiae Medicinae Sinicae
Año:
2014
Tipo del documento:
Artículo
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