Experimental study on guiding bone regeneration with bovine pericardium membrane / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 429-431, 2004.
Artículo
en Chino
| WPRIM
| ID: wpr-330027
ABSTRACT
<p><b>OBJECTIVE</b>To explore the feasibility of bovine pericardium used as a material for guiding bone regeneration.</p><p><b>METHODS</b>1 cm x 1 cm x 0.5 cm defects were created on both buccal sides of the mandibles of 11 dogs. One side was covered with Glutaraldehyde (GA) cross-linking bovine pericardium; no membrane covered side was used as control. The animals were sacrificed in 2 weeks, 4 weeks, 8 weeks and 16 weeks after operation to observe the repair of the bone defects.</p><p><b>RESULTS</b>(1) Wounds healed well in 10 dogs. Meanwhile, wounds in dogs of 16 weeks group healed badly and severe inflammatory response was found in bovine pericardium treated area. (2) The pericardium can be maintained in vivo for 16 weeks without absorption, there were only mild inflammatory cells invading. (3) The bone defects covered with bovine pericardium repaired better than control groups significantly.</p><p><b>CONCLUSION</b>(1) GA bovine pericardium have the effect on guiding bone regeneration in the repair of dog experimental bone defects and it is possible that the bovine pericardium will be used as a new kind of GBR material; (2) GA bovine pericardium has good biocompatibility.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pericardio
/
Fisiología
/
Cirugía General
/
Materiales Biocompatibles
/
Regeneración Ósea
/
Estudios de Factibilidad
/
Traumatismos Mandibulares
Límite:
Animales
Idioma:
Chino
Revista:
West China Journal of Stomatology
Año:
2004
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS