The method of monitoring sleep state and respiratory rhythm in freely moving rats / 中国应用生理学杂志

ABSTRACT

<p><b>AIM</b>To devise a new method for testing the animal model of sleep apnea syndrome (SAS).</p><p><b>METHODS</b>We simultaneously monitoring the respiratory wave through a micro-pressure transducer and the electrical signals of both electrocorticogram (ECoG) and electromyogram (EMG), for detecting the sleep-wake states and the respiratory rhythm in rats. The recording data are analyzed by the manual-computer work.</p><p><b>RESULTS</b>The ECoG and EMG signals are stable and easily to distinguish. We can accurately detect the sleep-wake state and the sleep apnea events in rats by these signals.</p><p><b>CONCLUSION</b>The method is reliable to test the small animal model of SAS, and is easily to operate.</p>