Clinical observation on effect of jieguxujin granule in promoting union of fracture / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the clinical effect of Jieguxujin granule (JGXJG) on fracture and its effect on serum content of calcitonin gene related peptide (CGRP).</p><p><b>METHODS</b>Four hundred patients with fracture were randomly divided into 2 groups, the JGXJG treated group and the control group treated with Sanqi tablet (SQT). Serum CGRP was tested with radioimmunoassay once every 3 days for 5 times, and X-ray examination was taken once each week for 10 weeks.</p><p><b>RESULTS</b>The healing time of fracture and osteotylus forming time in the JGXJG group was shorter than those in the SQT group significantly (P < 0.005). Serum CGRP content in JGXJG group was higher remarkably (P < 0.05, P < 0.01).</p><p><b>CONCLUSION</b>JGXJG showed evident effect in promoting union of fracture healing, it could also increase the CGRP content in serum.</p>