Effect of biminne on vascular permeability of nasal mucosa in allergic rhinitis rats / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 918-921, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-331951
ABSTRACT
<p><b>OBJECTIVE</b>To investigate whether the effect of Biminne on allergic rhinitis (AR) was through improving vascular permeability of nasal mucosa.</p><p><b>METHODS</b>Rat's model in Biminne-treated group and model group was induced by intraperitoneal injection of ovalbumin (OVA) and aluminum hydroxide gel suspension Biminne-treated rats were orally given Biminne suspension from the 8th day to the 17th day. On the 18th day, Evan's blue dye (EBD) in the nasal perfusate was detected to assess the vascular permeability.</p><p><b>RESULTS</b>EBD concentration was higher in the model rats than that in the normal rats, and lower in the Biminne-treated rats than that in the model rats (both P < 0.01).</p><p><b>CONCLUSION</b>Biminne could improve vascular permeability of nasal mucosa in sensitized rats, which may be the mechanism of its clinical effect on AR.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Ratas Endogámicas BN
/
Permeabilidad Capilar
/
Medicamentos Herbarios Chinos
/
Ovalbúmina
/
Rinitis Alérgica Perenne
/
Antialérgicos
/
Toxicidad
/
Inyecciones Intraperitoneales
/
Mucosa Nasal
Límite:
Animales
Idioma:
Chino
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Año:
2006
Tipo del documento:
Artículo
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