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Risk factors of obstructive sleep apnea hypopnea syndrome and sleep hypopnea in patients with growth hormone-secreting pituitary adenoma / 南方医科大学学报
Journal of Southern Medical University ; (12): 1501-1504, 2015.
Artículo en Chino | WPRIM | ID: wpr-333596
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the risk factors contributing to the development of obstructive sleep apnea hypopnea syndrome (OSAHS) and sleep hypopnea (SH) in patients with growth hormone-secreting pituitary adenoma (GHPA).</p><p><b>METHODS</b>A total of 85 patients with GHPA recruited strictly according to the inclusion and exclusion criteria underwent sleep monitoring overnight. Clinical manifestations, laboratory data and magnet resonance images were collected for analysis of the risk factors of GHPA and SH using binary logistic regression analysis.</p><p><b>RESULTS</b>The prevalence rate of OSAHS was 62.4% (53/85), and that of SH was 75.3% (64/85) in the recruited patients with GHPA. Regression analysis showed that age (OR=1.107) and BMI (OR=1.166) were the risk factors for OSAHS, and BMI (OR=1.334) was the risk factor of SH.</p><p><b>CONCLUSION</b>Ageing and an increased BMI are independent risk factors for OSAHS and SH in patients with GHPA. Preoperative sleep monitoring should be routinely conducted to ensure early diagnosis of OSAHS and SH, and patients with GHPA should be advised to control their body weight to lower the mortality associated with the respiratory system.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Sueño / Síndromes de la Apnea del Sueño / Índice de Masa Corporal / Prevalencia / Factores de Riesgo / Factores de Edad / Polisomnografía / Apnea Obstructiva del Sueño / Adenoma Hipofisario Secretor de Hormona del Crecimiento Tipo de estudio: Estudio de etiología / Estudio de prevalencia / Factores de riesgo / Estudio de tamizaje Límite: Humanos Idioma: Chino Revista: Journal of Southern Medical University Año: 2015 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Sueño / Síndromes de la Apnea del Sueño / Índice de Masa Corporal / Prevalencia / Factores de Riesgo / Factores de Edad / Polisomnografía / Apnea Obstructiva del Sueño / Adenoma Hipofisario Secretor de Hormona del Crecimiento Tipo de estudio: Estudio de etiología / Estudio de prevalencia / Factores de riesgo / Estudio de tamizaje Límite: Humanos Idioma: Chino Revista: Journal of Southern Medical University Año: 2015 Tipo del documento: Artículo