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Afebrile seizure subsequent to initial febrile seizure
Singapore medical journal ; : 349-352, 2012.
Artículo en Inglés | WPRIM | ID: wpr-334486
ABSTRACT
<p><b>INTRODUCTION</b>Febrile seizure (FS) is the most common paediatric neurological problem. The purpose of this study was to determine the frequency of afebrile seizures subsequent to FS in children with initial FS and to evaluate its risk factors.</p><p><b>METHODS</b>A prospective study was conducted on all children (age 6 months to 6 years) referred with initial FS to the Shahid Sadoughi Hospital, Yazd, Iran, between August 2004 and March 2006, who were followed up for at least 15 months for the occurrence of subsequent afebrile seizures.</p><p><b>RESULTS</b>161 boys and 120 girls (mean age 2.12 ± 1.33 years) were followed up for 34.1 ± 7.8 months. 87 (31%) patients had complex FS and 19 (6.7%) patients had subsequent afebrile seizure, with a mean occurrence time of 10.6 ± 6.4 months. Univariate analysis using chi-square test showed that initial FS within one hour of developing fever (p = 0.0001), neurodevelopmental delay (p = 0.0001), family history of epilepsy (p = 0.0001), recurrent FS (p = 0.003) and focal FS (p = 0.04) were risk factors for subsequent afebrile seizure. On multivariate analysis, neurodevelopmental delay (odds ratio [OR] 2.6, 95% confidence interval [CI] 2.3-3.4), initial FS within one hour of developing fever (OR 1.7, 95% CI 1.2-2.1) and family history of epilepsy (OR 1.5, 95% CI 1.1-1.9) were significant factors.</p><p><b>CONCLUSION</b>Special attention should be paid to children with FS during history-taking and developmental assessments to identify high-risk patients and those who might need prophylactic anticonvulsants.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Recurrencia / Convulsiones / Epidemiología / Incidencia / Estudios Prospectivos / Factores de Riesgo / Convulsiones Febriles / Irán Tipo de estudio: Estudio de etiología / Estudio de incidencia / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Niño / Child, preschool / Femenino / Humanos / Lactante / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: Singapore medical journal Año: 2012 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Recurrencia / Convulsiones / Epidemiología / Incidencia / Estudios Prospectivos / Factores de Riesgo / Convulsiones Febriles / Irán Tipo de estudio: Estudio de etiología / Estudio de incidencia / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Niño / Child, preschool / Femenino / Humanos / Lactante / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: Singapore medical journal Año: 2012 Tipo del documento: Artículo