Genome sequencing and analysis of foot-and-mouth disease virus Asia1/YNBS/58 strain / 病毒学报
Chinese Journal of Virology
;
(6): 407-411, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-334874
ABSTRACT
The full-length genomic sequence of foot-and-mouth disease virus (FMDV) Asia1/YNBS/58 strain was determined by RT-PCR and compared with other 17 reference strains. The results showed that the complete genome of Asia1/YNBS/58 was 8164nt long including a 1061-nt 5' untranslated region (UTR), a 6990-nt open reading frame (ORF), and a 113-nt 3'UTR. The homology analysis indicated that the UTR regions and non-structural proteins were more conserved than the structural proteins in FMDV. VP1 exhibited the lowest conservation and VP4 was exceptionally conserved. The VP1-, VP2-, and VP3-based phylogenetic trees were divided into distinct clusters according to different serotypes, while the other gene-based phylogenetic trees exhibited some degree of intercross among serotypes. This study is the first description of the full-length genomic sequence of FMDV Chinese serotype Asia1.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Filogenia
/
Química
/
Genoma Viral
/
Análisis de Secuencia de ADN
/
Regiones no Traducidas 3'
/
Virus de la Fiebre Aftosa
/
Proteínas de la Cápside
/
Genética
Idioma:
Chino
Revista:
Chinese Journal of Virology
Año:
2007
Tipo del documento:
Artículo
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