Progress in research on pathogenic genes and gene therapy for inherited retinal diseases / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 118-123, 2017.
Artículo
en Chino
| WPRIM
| ID: wpr-335169
ABSTRACT
Inherited retinal diseases (IRDs), including retinitis pigmentosa, Usher syndrome, Cone-Rod degenerations, inherited macular dystrophy, Leber's congenital amaurosis, Leber's hereditary optic neuropathy are the most common and severe types of hereditary ocular diseases. So far more than 200 pathogenic genes have been identified. With the growing knowledge of the genetics and mechanisms of IRDs, a number of gene therapeutic strategies have been developed in the laboratory or even entered clinical trials. Here the progress of IRD research on the pathogenic genes and therapeutic strategies, particularly gene therapy, are reviewed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Enfermedades de la Retina
/
Terapéutica
/
Terapia Genética
/
Ensayos Clínicos como Asunto
/
Resultado del Tratamiento
/
Predisposición Genética a la Enfermedad
/
Investigación Biomédica
/
Genética
/
Métodos
/
Mutación
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Medical Genetics
Año:
2017
Tipo del documento:
Artículo
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