Cytochrome P450 drug interactions with statin therapy
Singapore medical journal
;
: 131-135, 2013.
Artículo
en Inglés
| WPRIM
| ID: wpr-335433
ABSTRACT
Statins are commonly used in the treatment of hyperlipidaemia. Although the benefits of statins are well-documented, they have the potential to cause myopathy and rhabdomyolysis due to the complex interactions of drugs, comorbidities and genetics. The cytochrome P450 family consists of major enzymes involved in drug metabolism and bioactivation. This article aims to highlight drug interactions involving statins, as well as provide updated recommendations and approaches regarding the safe and appropriate use of statins in the primary care setting.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Lovastatina
/
Colchicina
/
Claritromicina
/
Debilidad Muscular
/
Inhibidores de Hidroximetilglutaril-CoA Reductasas
/
Creatina Quinasa
/
Interacciones Farmacológicas
/
Citocromo P-450 CYP3A
/
Seguridad del Paciente
/
Mialgia
Tipo de estudio:
Guía de Práctica Clínica
Límite:
Anciano
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Singapore medical journal
Año:
2013
Tipo del documento:
Artículo
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