Immunophenotypic characteristics of multiple myeloma cells / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 226-228, 2002.
Artículo
en Chino
| WPRIM
| ID: wpr-337604
ABSTRACT
To investigate the immunophenotypic characteristics of multiple myeloma (MM) cells, 20 bone marrow samples from patients with multiple myeloma were analyzed by flow cytometry with three-color direct immunofluorescence staining. Results showed that all of myeloma cells expressed bright CD38, dim or negative CD45 and negative CD19. Most of the cells were CD56(+) and a small portions were ckappa(+) or clambda(+), or CD20(+). The phenotypes of normal plasmocyte, CD19(+) and CD56(-), except CD56(-) in one-third samples, were not appeared in all detected samples. It was concluded that the surface marker analysis of myeloma cells is a useful tool for diagnosis and further evaluating prognosis of multiple myeloma.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Células de la Médula Ósea
/
Glicoproteínas de Membrana
/
Antígenos CD
/
Inmunofenotipificación
/
Antígenos Comunes de Leucocito
/
Antígeno CD56
/
Antígenos CD20
/
Antígenos CD19
/
ADP-Ribosil Ciclasa
/
Alergia e Inmunología
Tipo de estudio:
Estudio pronóstico
Límite:
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Journal of Experimental Hematology
Año:
2002
Tipo del documento:
Artículo
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