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Toxicogenomics and its application in safety evaluation of traditional Chinese medicine / 中国中药杂志
Article en Zh | WPRIM | ID: wpr-337907
Biblioteca responsable: WPRO
ABSTRACT
Toxicogenomics (TGx) refers to a set of technologies that assess genome-wide responses after toxic agent exposure. Altered gene expression patterns that are caused by specific exposures reveal how toxicants may disrupt cellular processes and lead to side effects. Development and application of " omics" technology facilitate the toxicogenomic research which sharing and interpretation of the enormous amount of biological information generated in toxicologic field. In recent years TGx has been widely valued and successfully applied as an effective research tool to evaluate the toxic effects of traditional Chinese medicine (TCM). Here we reviewed current progress in the field of TGx and focused on its application in traditional Chinese medicine safety evaluation, especially in revealing the mechanism, finding potential toxic biomarkers and studying compatibility detoxification of TCM.
Asunto(s)
Texto completo: 1 Índice: WPRIM Asunto principal: Seguridad / Toxicogenética / Medicina Tradicional China Tipo de estudio: Diagnostic_studies Idioma: Zh Revista: China Journal of Chinese Materia Medica Año: 2015 Tipo del documento: Article
Texto completo: 1 Índice: WPRIM Asunto principal: Seguridad / Toxicogenética / Medicina Tradicional China Tipo de estudio: Diagnostic_studies Idioma: Zh Revista: China Journal of Chinese Materia Medica Año: 2015 Tipo del documento: Article